Description:
Saxagliptin hydrate is a selective and reversible DPP4 inhibitor. It demonstrates greater specificity for DPP4 than for either the DPP8 or DPP9 enzymes. It reduces the degradation of the incretin hormone glucagon-like peptide-1, thereby enhancing its actions, and is associated with improved β-cell function and suppression of glucagon secretion.
- Molecular Weight:333.43
- Purity:>98%
Molecular Formula:
C18H27N3O3
Canonical SMILES:
C1C2CC2N(C1C#N)C(=O)C(C34CC5CC(C3)CC(C5)(C4)O)N.O
InChI:
InChI=1S/C18H25N3O2.H2O/c19-8-13-2-12-3-14(12)21(13)16(22)15(20)17-4-10-1-11(5-17)7-18(23,6-10)9-17;/h10-15,23H,1-7,9,20H2;1H2/t10?,11?,12-,13?,14-,15?,17?,18?;/m0./s1
InChIKey:
AFNTWHMDBNQQPX-VZBUNICMSA-N
Synonyms:
BMS-477118 hydrate; BMS 477118 hydrate; BMS477118 hydrate; Onglyza hydrate Más detalles se encuentran
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